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Postdoc: Single-Cell Biology [Ma Lab]

Multiple positions are available after in the Ma Lab in the Department of Genetics and Genomic Sciences at Icahn School of Medicine at Mount Sinai in the heart of New York City.

What We Do

Our work involves innovating experimental and computational tools to investigate epigenetic mechanisms of gene regulation in single-cells across dynamic cell fate transitions. The importance of our work is in helping to understand the molecular mechanisms and functional implications in the normal development and diverse diseases. Leveraging cutting-edge technologies and large cohorts of disease samples, our research directions include but are not limited to technology development, gene regulation, cell fate mapping, and disease mechanism investigation.

More specifically, we are keen on developing experimental sequencing tools—SHARE-seq, MID-RRBS, SurfaceChIP-seq, and Spatial-ATAC-seq—to profile the epigenomes and transcriptomes within rare populations, single-cells or in situ (Cell 2020; Sci. Adv. 2018; Nat. Biomed. Eng. 2018; bioRxiv 2021). We also build computational workflows (Nature Commun. 2020; Cell 2020; Nature Methods 2020) and apply these tools to investigate cell fate determination (Nat. Neurosci. accepted) and perturbed cell states (Nature 2021; Nature 2020), such as tumor progression (Cancer Discovery 2021; Cancer Cell 2020).

Your Qualifications

Postdoc candidates should have a Ph.D. or MD/Ph.D. degree in cell biology, molecular biology, genetics, genomics, bioengineering, biomedical engineering, computational biology, or related field. BA/BS or MA/MS will be considered for Research Associate. Candidates with computational and/or experimental background are both welcome. He/she should have the ability to work independently and communicate with colleagues with varying expertise.

How to Apply

Applicants who are interested in this position should email 1) a brief summary of research interests 2) a CV, including a complete list of publications, 3) names and contact information of three references to Dr. Ma ( We look forward to seeing you in NYC!