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Postdoc: Microbiology, Microbial Engineering, Systems Biology [W. Jiang Lab]

The Jiang lab at Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York is inviting applications for Postdoctoral Research Scientist and Research Associate positions in microbiology, microbial engineering and systems biology. We welcome individuals with experimental and/or computational backgrounds to apply. Candidates with specialties in antimicrobial resistance, single-cell RNA-seq and various systems biology approaches are highly sought after. 

Research Focus

Over the last decade, we have developed revolutionary technologies that enhance the precisionthroughput and resolution for bacterial genomics and transcriptomics. These include development of the very first CRISPR-Cas9 genome editing (Nature Biotech 2013, >2,000 citation) and gene expression modulation technology (Nucleic Acids Research 2013, >1,000 citation) in bacteria; a high-throughput bacterial functional genomics platform called CALM (Cell 2020); and the first bacterial high-throughput single-cell RNA sequencing (scRNA-seq) technology called PETRI-seq (Nature Microbiol 2020). Proven to be reproducible by labs all around the world, these technologies have substantially expanded scientists’ ability to solve fundamental and applied questions in complex microbial systems. [Google Scholar]

One long-term goal of the Jiang Lab is to continue developing enabling technologies such as CRISPR genome editing, functional genomics and various single-cell tools, and expanding them to a wide range of non-model bacterial species of clinical and industrial importance. By applying these technologies, we aim to tackle diverse systems-level problems in microbiology, such as understanding antimicrobial resistance (Cell 2020)genetic interaction networksmicrobial heterogeneity (Nature Microbiol 2020)phage-bacteria interactions (Nature 2014Nature Biotech 2015Cell 2016), and engineering microbes to promote human health.

About the PI

Dr. Wenyan Jiang is an assistant professor in the Department of Genetics and Genomic SciencesIcahn School of Medicine at Mount Sinai. He is also affiliated with the Department of MicrobiologyIcahn Genomics Institute and Precision Immunology Institute. His lab will start in January 2023.

Wenyan did his PhD at Rockefeller University with HHMI investigator and microbiologist, Luciano Marraffini. He then received his postdoctoral training at Columbia University with systems biologist, Saeed Tavazoie. Wenyan’s major contribution to biological sciences includes development of the first CRISPR-Cas9 genome editing technology in bacteria, and the first bacterial high-throughput single-cell RNA sequencing technology. Some awards received by Wenyan include the NIH Pathway to Independence Award (K99/R00), Blavatnik Regional Awards for Young Scientist (2021), Jane Coffin Childs Fellowship (2017), and Weintraub Graduate Student Award (2016).

Outside of biomedical sciences, Wenyan is a learner of multiple foreign languages, and a writer of prose, poetry and options contracts.

About Mount Sinai

Mount Sinai is one of the nation’s top biomedical institutions in research, patient care, and education. With a faculty of more than 3,400 in 38 clinical and basic science departments and centers, Mount Sinai has made major recent investments to attract world class expertise and build cutting-edge resources to fuel advanced research in biomedical data science and advanced technology development. Icahn School of Medicine at Mount Sinai (ISMMS) is ranked #11 in the Best Medical Schools by US News (2023). Department of Genetics and Genomic Sciences (GGS) is ranked #2 nationally based on NIH funding (2021). 


  • Strong expertise in microbial genomic sciences such as CRISPR genomics and bacterial high-throughput single cell transcriptomics
  • Strong mentorship in both research and career development
  • Access to large-scale clinical microbiology samples and data at Mount Sinai
  • World-class next generation sequencing (NGS) platform and high performance computing (HPC) cluster [Mount Sinai Genomics Core Facility] [Mount Sinai Center for Advanced Genomic Technology]
  • Compensations are highly competitive with subsidized housing in New York City

Your Qualifications

Postdoc candidates should have a PhD, MD or equivalent degree in biomedical sciences. Candidates with BA/BS or MA/MS will be considered for Research Associate positions.


Please send your CV and the names of three references to Dr. Wenyan Jiang (