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Postdoc: Long-Reads, Alternative Splicing, and Human Diseases [Fang Lab]

The Fang Lab has rich experience in long read sequencing technology (both PacBio and Oxford Nanopore), systems biology and precision medicine. We use long read sequencing to make new discoveries from the human genome, epigenome and transcriptome (Genome Research, 2018; Nature Genetics, 2019; Science, 2021 in press). We also pioneered the fast-growing field of bacterial epigenomics (Nature Biotechnology, 2012; Nature Reviews Genetics, 2018, Nature Microbiology, 2020), and the use of DNA methylation for high-resolution microbiome analysis (Nature Biotechnology, 2018; Nature Methods, 2021).


We are looking for highly motivated Postdoctoral Fellows to:

  • develop innovative long read sequencing-based methods to study alternative splicing;
  • make new discoveries in basic biology and translate them into medical impact, in close collaboration with Kristen Brennand Lab @Yale.

Successful candidates will have unique opportunities with:

  • a highly interdisciplinary and innovative lab culture where members with dry/wet background closely discuss and learn from each other.
  • our unique expertise in long read sequencing, multi-omics, rich clinical samples and strong collaborators.
  • take the lead role in projects developing cutting edge, pioneering technologies with high biomedical and clinical impact.
  • strong mentorship in both research and career development.
  • Compensations are highly competitive with subsidized housing in New York City.


  • Candidates with computational and/or experimental background are both welcome.
  • Previous research experience in alternative splicing is required.
  • Previous experience in long read sequencing is a plus but not required;
  • Ability to learn and master new knowledge and technologies,
  • Abilities to lead an independent research direction while adapting to a collaborative environment,
  • An innovative yet critical thinker.

How to apply

Please send the following to

  • A brief cover letter
  • CV with a list of publications
  • PDF files for the papers in which you are first/co-first author